PhD Opportunity in Fungal OMICS
Applications are invited for a PhD position within a newly established Fungal OMICS research project, funded by Research Ireland, in the Genome Evolution Laboratory of Prof David Fitzpatrick at Maynooth University. The laboratory has an established reputation in fungal comparative genomics, transcriptomics, and proteomics.
Infectious diseases are one of the major causes of mortality and disability worldwide. It is estimated that 300 million people are affected by an invasive fungal disease annually and more than 1.5 million die from these infections. In recent years antifungal resistance has been on the rise, and this is exacerbated as global warming is also leading to emerging invasive fungal diseases such as Candida auris. The World Health Organisation has published a fungal priority pathogen list, and this list includes six Candida spp. Candida spp. are commensal yeasts but can cause Candidiasis leading to invasive candidiasis (IC) which are bloodstream infections with high mortality rates. Overall, C. albicans is the most common pathogen in most clinical settings but other species are on the rise. The purpose of this research proposal is to (i) gain mechanistic insights into the genetic and molecular alterations that can lead to antifungal resistance in Candida species highlighted on the WHO fungal priority pathogen list. (ii) We wish to thoroughly investigate plant-based antimicrobials for efficacy. Furthermore, their potential mechanism of action against antifungal susceptible and resistant Candida strains will be elucidated using comparative genomics, transcriptomics and proteomics.
Candidate Profile
This position is ideally suited to candidates with a strong interest in microbiology, genetics, genomics, and evolutionary biology. Applicants with demonstrable experience in bioinformatics are particularly encouraged to apply.
Eligibility and Funding
Candidates must be available to commence the position in September 2025. Applicants should hold, or be expected to obtain, a first-class or upper second-class (2.1) honours degree (BSc) or a master’s degree (MSc) in microbiology, genetics, bioinformatics, genome science, biotechnology, or a related discipline.
The studentship includes full EU tuition fees and a tax-free annual stipend of €25,000 for four years.
Application Procedure:
To apply, please email Prof David Fitzpatrick with the subject line: “Candida/PhD/2025”.
The closing date is Wednesday the 11th of June 2025, 5pm.
Applications must include a single PDF document containing the following:
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Curriculum Vitae, including academic background.
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Transcripts of degree results (or current results, if still completing studies).
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List of publications, conference presentations, or prior research experience (if applicable).
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A motivation letter (1–2 pages) outlining research interests and relevant skills.
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Contact details for two academic referees.
Roinn Bitheolaíochta Ollscoil Mhá Nuad, Ollscoil Mhá Nuad, Maigh Nuad, Co. Chill Dara, Éire.
Maynooth University Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.
T +353 1 708 6844
E David.fitzpatrick@mu.ie
W maynoothuniversity.ie/biology
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